STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bace2Beta-secretase 2; Belongs to the peptidase A1 family. (506 aa)    
Predicted Functional Partners:
LOC101078447
Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O); Belongs to the APP family.
    
 0.786
APP
Amyloid beta precursor protein.
    
 0.710
LOC101078322
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
   
 0.599
LOC101061571
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
   
 0.599
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.579
LOC101078557
Uncharacterized protein.
    
 0.579
LOC101074958
Uncharacterized protein.
    
 0.579
aplp2
Amyloid beta (A4) precursor-like protein 2.
    
 0.579
sez6l
Seizure related 6 homolog (mouse)-like.
   
 0.566
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
     
 0.562
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.