Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
parp3Poly [ADP-ribose] polymerase. (528 aa)    
Predicted Functional Partners:
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.928
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.928
LOC101074856
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.928
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.928
LOC101065337
Peptidase S1 domain-containing protein.
   
 
  0.902
LOC101070721
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.902
parp1
Poly [ADP-ribose] polymerase.
    
 
 0.861
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.808
rfc4
Replication factor C (activator 1) 4.
   
 0.777
rfc5
Replication factor C (activator 1) 5.
   
 0.777
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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