Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101074228Interferon regulatory factor 4b. (450 aa)    
Predicted Functional Partners:
LOC101075171
Interferon regulatory factor.
  
0.706
LOC105419331
Si:ch211-207e14.4.
      
 0.700
spi1
Spi-1 proto-oncogene b.
   
 
 0.688
il10
Interleukin 10.
   
 
 0.657
plk3
Serine/threonine-protein kinase PLK.
   
 0.581
iscu
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
    
 
 0.543
LOC101070222
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.527
ppp2r1b
Protein phosphatase 2, regulatory subunit A, beta b.
    
  0.521
batf
Basic leucine zipper transcription factor, ATF-like.
   
 0.505
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.503
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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