Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (299 aa)    
Predicted Functional Partners:
prkaa1
Non-specific serine/threonine protein kinase.
   
 0.992
prkaa2
Non-specific serine/threonine protein kinase.
   
 0.991
Prkag2
Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.
   
 0.989
prkag3
Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.
   
 0.987
LOC101064981
Protein kinase, AMP-activated, gamma 3a non-catalytic subunit.
   
 0.987
prkag1
Protein kinase, AMP-activated, gamma 1 non-catalytic subunit.
   
 0.987
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.974
LOC101067210
Si:ch73-62l21.1.
    
 0.962
acaca
Acetyl-CoA carboxylase alpha.
    
 0.952
acacb
Acetyl-CoA carboxylase beta.
    
 0.952
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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