Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
a2d1ARAdrenergic, alpha-2D-, receptor a. (375 aa)    
Predicted Functional Partners:
GNG4
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.
    
  0.775
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.775
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.771
LOC101077498
Guanine nucleotide binding protein (G protein), beta 5b.
    
  0.771
LOC101069051
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
    
  0.771
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.771
LOC101074575
Guanine nucleotide binding protein (G protein), beta 5a.
    
  0.771
gnb2
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.771
LOC101062666
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  0.766
gng3
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.760
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (42%) [HD]