Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vps26bVPS26, retromer complex component B. (346 aa)    
Predicted Functional Partners:
vps26a
VPS26, retromer complex component A.
  
0.990
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.982
LOC101078809
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.961
LOC101078809-2
VPS35 retromer complex component.
   
 0.961
LOC101067116
Uncharacterized protein.
  
  
 
0.900
LOC101074952
Sorting nexin 12.
    
 0.896
snx3
Sorting nexin 3.
    
 0.896
LOC101077110
Sorting nexin 1a.
   
 
 0.818
snx2
Sorting nexin 2.
   
 
 0.818
SNX27
Sorting nexin 27.
   
 
 0.794
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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