STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcp1aDecapping mRNA 1A. (497 aa)    
Predicted Functional Partners:
xrn1
5'-3' exoribonuclease 1.
    
 0.994
LOC105417758
Decapping mRNA 1B.
  
 
0.990
edc3
Enhancer of mRNA decapping 3 homolog (S. cerevisiae).
   
 0.980
Dcp2
DCP2 domain-containing protein.
    
 0.980
LOC101068749
Proline-rich nuclear receptor coactivator 2.
    
 0.962
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family.
   
 0.938
LOC101070680
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.938
LOC101064659
Uncharacterized protein.
    
 0.924
UPF1
Putative regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an rent1-rent2-rent3 surveillance complex is believed to activate NMD (By similarity).
    
 0.924
patl1
PAT1 homolog 1, processing body mRNA decay factor.
    
 0.908
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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