Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ctnnb1Catenin (cadherin-associated protein), beta 1. (781 aa)    
Predicted Functional Partners:
LOC101070964
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.999
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
   
 0.999
lef1
Lymphoid enhancer-binding factor 1.
    
 0.999
tcf7
Transcription factor 7.
    
 0.999
LOC101063744
APC membrane recruitment protein 1.
    
 0.998
fbxw11
F-box and WD repeat domain containing 11b.
    
 0.997
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.996
apc
APC regulator of WNT signaling pathway.
   
 0.995
LOC101062949
Adenomatous polyposis coli protein 2-like isoform X1.
   
 0.995
ctnna1
Catenin (cadherin-associated protein), alpha 1.
   
 0.994
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.