Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101075979PDZ domain containing 3b. (527 aa)    
Predicted Functional Partners:
LOC101064607
Uncharacterized protein; Belongs to the peptidase S1 family.
     
 0.604
LOC101071414
Zgc:92313; Belongs to the peptidase S1 family.
     
 0.604
LOC101071869
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
    
 
 0.584
cask
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
 0.533
ift88
Intraflagellar transport 88 homolog.
    
 0.525
LOC101064934
Uncharacterized protein.
   
  
 0.514
traf3ip1
TNF receptor-associated factor 3 interacting protein 1.
    
 0.501
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.496
rasl10a
RAS-like, family 10, member A.
    
 0.496
ift172
Uncharacterized protein.
    
 0.490
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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