| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fancm | LOC101078394 | ENSTRUP00000024507 | ENSTRUP00000024018 | ERCC4 domain-containing protein. | RPA_C domain-containing protein. | 0.894 |
| Fancm | atrip | ENSTRUP00000024507 | ENSTRUP00000008639 | ERCC4 domain-containing protein. | Uncharacterized protein. | 0.979 |
| Fancm | blm | ENSTRUP00000024507 | ENSTRUP00000078695 | ERCC4 domain-containing protein. | BLM RecQ like helicase. | 0.998 |
| Fancm | pcna | ENSTRUP00000024507 | ENSTRUP00000052987 | ERCC4 domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.988 |
| Fancm | rad51 | ENSTRUP00000024507 | ENSTRUP00000052909 | ERCC4 domain-containing protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.971 |
| Fancm | rpa1 | ENSTRUP00000024507 | ENSTRUP00000008475 | ERCC4 domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.969 |
| Fancm | rpa2 | ENSTRUP00000024507 | ENSTRUP00000074223 | ERCC4 domain-containing protein. | Replication protein A2. | 0.894 |
| Fancm | rpa3 | ENSTRUP00000024507 | ENSTRUP00000056690 | ERCC4 domain-containing protein. | Replication protein A3. | 0.831 |
| Fancm | top3a | ENSTRUP00000024507 | ENSTRUP00000081442 | ERCC4 domain-containing protein. | DNA topoisomerase 3-alpha. | 0.995 |
| Fancm | top3a-2 | ENSTRUP00000024507 | ENSTRUP00000063973 | ERCC4 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.995 |
| LOC101078394 | Fancm | ENSTRUP00000024018 | ENSTRUP00000024507 | RPA_C domain-containing protein. | ERCC4 domain-containing protein. | 0.894 |
| LOC101078394 | atrip | ENSTRUP00000024018 | ENSTRUP00000008639 | RPA_C domain-containing protein. | Uncharacterized protein. | 0.861 |
| LOC101078394 | blm | ENSTRUP00000024018 | ENSTRUP00000078695 | RPA_C domain-containing protein. | BLM RecQ like helicase. | 0.941 |
| LOC101078394 | pcna | ENSTRUP00000024018 | ENSTRUP00000052987 | RPA_C domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.899 |
| LOC101078394 | rad51 | ENSTRUP00000024018 | ENSTRUP00000052909 | RPA_C domain-containing protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.897 |
| LOC101078394 | rpa1 | ENSTRUP00000024018 | ENSTRUP00000008475 | RPA_C domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.990 |
| LOC101078394 | rpa2 | ENSTRUP00000024018 | ENSTRUP00000074223 | RPA_C domain-containing protein. | Replication protein A2. | 0.905 |
| LOC101078394 | rpa3 | ENSTRUP00000024018 | ENSTRUP00000056690 | RPA_C domain-containing protein. | Replication protein A3. | 0.995 |
| LOC101078394 | top3a | ENSTRUP00000024018 | ENSTRUP00000081442 | RPA_C domain-containing protein. | DNA topoisomerase 3-alpha. | 0.924 |
| LOC101078394 | top3a-2 | ENSTRUP00000024018 | ENSTRUP00000063973 | RPA_C domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.924 |
