Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
atp7aATPase copper transporting alpha. (1519 aa)    
Predicted Functional Partners:
Atox1
HMA domain-containing protein.
    
 0.998
ccs
Copper chaperone for superoxide dismutase.
  
 0.986
pdzd11
PDZ domain containing 11.
    
 0.976
commd1
Copper metabolism (Murr1) domain containing 1.
    
 
 0.927
H2V4V2_TAKRU
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.889
brca1
Uncharacterized protein.
      
 0.881
tbx4
T-box transcription factor 4.
   
  
 0.797
slc31a1
Solute carrier family 31 member 1.
    
 
 0.790
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.750
RAG2
Recombination-activating protein 2.
      
 0.741
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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