Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNIKTRAF2 and NCK interacting kinase. (1294 aa)    
Predicted Functional Partners:
nck2
Cytoplasmic protein.
    
 
 0.598
nck1
Cytoplasmic protein.
    
 
 0.598
nrg1
Pro-neuregulin-1, membrane-bound isoform isoform X1.
    
 
 0.584
lats1
Large tumor suppressor kinase 1.
    
 
 0.524
lats2
Large tumor suppressor kinase 2.
    
 
 0.524
txn
Thioredoxin domain-containing protein.
     
  0.469
LOC101075562
Thioredoxin; Belongs to the thioredoxin family.
     
  0.469
traf4
TNF receptor-associated factor.
    
 
 0.468
disc1
Uncharacterized protein.
    
 
 0.463
dao
D-amino-acid oxidase, tandem duplicate 2.
      
 0.458
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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