Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arhgef37Rho guanine nucleotide exchange factor (GEF) 37. (751 aa)    
Predicted Functional Partners:
bin3
Bridging integrator 3.
    
 
 0.782
LOC101067976
MCF.2 cell line derived transforming sequence-like 2.
     
 0.752
LOC101077791
Uncharacterized protein.
    
 0.665
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.650
mrps22
Mitochondrial ribosomal protein S22.
      
 0.630
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.621
arhgef12
Rho guanine nucleotide exchange factor (GEF) 12a.
   
 
 0.621
LOC101070544
Rho guanine nucleotide exchange factor (GEF) 25b.
     
 0.562
LOC101065834
Rho guanine nucleotide exchange factor (GEF) 39.
    
 0.548
LOC101076147
Uncharacterized protein.
    
 0.544
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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