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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101080133Potassium channel subfamily K member. (318 aa)    
Predicted Functional Partners:
kcnh6
Potassium voltage-gated channel, subfamily H (eag-related), member 6a.
    
 
 0.584
KCNC4
Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family.
   
  
 0.580
atp1b1
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
  
 0.575
hvcn1
Hydrogen voltage-gated channel 1.
      
 0.573
slc20a1
Solute carrier family 20 (sodium-dependent phosphate transporter).
      
 0.573
LOC101066134
Magnesium transporter 1.
      
 0.573
scn1b
Sodium channel, voltage-gated, type I, beta b.
    
 
 0.553
ENSTRUP00000061612
Piezo-type mechanosensitive ion channel component 1.
   
  
 0.551
H2SAY2_TAKRU
Piezo_RRas_bdg domain-containing protein.
   
  
 0.551
LOC101064410
Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.455
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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