Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)    
Predicted Functional Partners:
rapgef1
Rap guanine nucleotide exchange factor (GEF) 1b.
    
 0.996
dock1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.993
gab1
GRB2-associated binding protein 1.
    
 0.986
LOC101078435
PH domain-containing protein.
    
 0.986
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.981
pxn
Uncharacterized protein.
    
 0.981
abl2
Tyrosine-protein kinase.
    
 0.976
abl1
Tyrosine-protein kinase.
    
 0.976
LOC101073575
Mitogen-activated protein kinase.
    
 0.957
LOC101070190
Mitogen-activated protein kinase.
    
 0.957
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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