Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
cnp-3C-type natriuretic peptide 3; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family. (158 aa)    
Predicted Functional Partners:
cnp-1
C-type natriuretic peptide 1; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.
  
   
 0.838
cnp-1-2
Takifugu rubripes C-type natriuretic peptide-1 (cnp-1), mRNA.
  
   
 0.838
nppb
Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.
      
 0.749
nppc
C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.
      
 0.630
sh2d1a
SH2 domain containing 1A duplicate b.
      
 0.476
nppa
Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.
      
 0.457
wdr45
WD repeat domain 45.
      
 0.425
wdr45b
WD repeat domain 45B.
      
 0.425
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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