Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sik3SIK family kinase 3. (1308 aa)    
Predicted Functional Partners:
YWHAE
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.676
LOC101077875
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
 0.676
nalcn
Sodium leak channel, non-selective.
   
  
 0.650
ankle2
Ankyrin repeat and LEM domain containing 2.
    
 0.635
gins4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
    
   0.625
vps37a
VPS37A subunit of ESCRT-I.
      
 0.620
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family.
    
 0.610
ywhaq
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.610
LOC101063623
14_3_3 domain-containing protein.
    
 0.610
ywhaz
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.610
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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