STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sik3SIK family kinase 3. (1308 aa)    
Predicted Functional Partners:
nalcn
Sodium leak channel, non-selective.
     
 0.507
cask
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
0.462
LOC101067395
X-linked inhibitor of apoptosis.
   
 
 0.409
LOC101075035
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
   
 0.406
LOC101067379
Uncharacterized protein.
   
 0.406
LOC101078875
Diencephalon/mesencephalon homeobox 1a.
      
 0.403
pox1
Uncharacterized protein.
      
 0.403
tshr
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
      
 0.403
LOC101078148
Luteinizing hormone/choriogonadotropin receptor.
      
 0.403
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.