Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101073645Serine peptidase inhibitor, Kunitz type 1 b. (502 aa)    
Predicted Functional Partners:
hgfac
HGF activator.
    
 0.850
LOC101064315
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.660
LOC101078862
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.660
LOC101073986
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.660
st14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
   
 0.551
LOC101074247
Uncharacterized protein.
   
 0.551
GHITM
Growth hormone inducible transmembrane protein; Belongs to the BI1 family.
      
 0.483
nudt14
Nudix (nucleoside diphosphate linked moiety X)-type motif 14.
      
 0.443
banp
BTG3 associated nuclear protein.
      
 0.437
actr10
Actin related protein 10; Belongs to the actin family.
   
  
 0.437
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.