Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5. (886 aa)    
Predicted Functional Partners:
pik3cg
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.997
H2S720_TAKRU
PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.
   
 0.997
GNG4
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.
    
 0.935
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.935
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.920
pik3r6
Uncharacterized protein.
   
 
0.920
LOC101067191
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.920
pik3cb
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.920
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.920
ENSTRUP00000078829
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.920
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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