Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sptbn4Spectrin beta chain; Belongs to the spectrin family. (2444 aa)    
Predicted Functional Partners:
sptan1
Uncharacterized protein.
   
 0.924
add1
Adducin 1 (alpha).
    
 
 0.591
LOC101064298
Uncharacterized protein.
    
 
 0.591
LOC100462937
Adducin 2 (beta).
    
 
 0.591
ANK2
Ankyrin 2b, neuronal.
   
 0.582
LOC101067381
Ankyrin 3a.
   
 0.582
ank1
Ankyrin 1, erythrocytic a.
   
 0.582
ENSTRUP00000083487
Uncharacterized protein.
   
 0.582
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.564
actr10
Actin related protein 10; Belongs to the actin family.
    
 0.560
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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