Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101079659Adrenoceptor alpha 1Ab. (454 aa)    
Predicted Functional Partners:
LOC101071876
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.967
gna12
G protein subunit alpha 12.
    
 0.967
LOC101065558
Uncharacterized protein.
    
 0.967
LOC101066291
Uncharacterized protein.
    
 0.948
LOC101063826
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.948
LOC101076768
Uncharacterized protein.
    
  0.911
LOC101077978
Guanine nucleotide binding protein (G protein), alpha 14.
    
  0.911
LOC101062666
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.846
edn1
Endothelin 1.
    
 0.826
LOC101066066
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.821
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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