Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101079555Lysine (K)-specific demethylase 4C. (1606 aa)    
Predicted Functional Partners:
KDM1B
Lysine demethylase 1B.
   
 0.812
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.728
atm
TAN domain-containing protein.
   
 
 0.597
pias4
Protein inhibitor of activated STAT, 4a.
   
 0.554
nsd2
Nuclear receptor binding SET domain protein 2.
     
 0.539
rps27a
Ribosomal protein S27a.
     
  0.539
LOC101067852
Uncharacterized protein.
    
 0.537
LOC101080066
Androgen receptor.
    
 0.537
rad50
RAD50 homolog, double strand break repair protein.
     
  0.532
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
     
  0.516
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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