Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wasf3WASP family member 3b. (499 aa)    
Predicted Functional Partners:
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 0.986
cyfip2
Cytoplasmic FMR1 interacting protein 2.
   
 0.985
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.983
nckap1
NCK-associated protein 1.
    
 0.972
LOC101069559
Abl-interactor 1b.
   
 0.971
ABI1
Abl-interactor 1a.
   
 0.971
nckap1l
NCK associated protein 1 like.
    
 0.971
LOC101069102
Actin, cytoplasmic 3, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
    
 0.951
RAC1
Uncharacterized protein.
   
 0.950
LOC101067160
Rac family small GTPase 1b.
   
 0.950
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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