Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
s1pr5G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (566 aa)    
Predicted Functional Partners:
LOC101063726
Si:dkey-26c10.5.
    
 0.731
pdgfrb
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]
   
 
 0.522
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.468
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.468
gnb2
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.468
LOC101062348
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.468
dlx2
Distal-less homeobox 2b.
      
 0.426
thbs1
Uncharacterized protein.
    
 0.400
thbs2
Thrombospondin 2a.
    
 0.400
LOC101062487
Thrombospondin 1b.
    
 0.400
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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