STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cxxc4CXXC finger 4. (289 aa)    
Predicted Functional Partners:
dvl3
Dishevelled segment polarity protein 3a.
    
 0.906
dvl2
Dishevelled segment polarity protein 2.
    
 0.906
dvl1
Dishevelled segment polarity protein 1a.
    
 0.906
LOC105419947
DNA N6-methyl adenine demethylase-like isoform X1.
     
 
0.900
LOC101072272
Programmed cell death 4a.
      
 0.701
topors
E3 ubiquitin-protein ligase Topors.
      
 0.701
mtap
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
      
 0.701
tet2
Tet methylcytosine dioxygenase 2.
    
 
 0.620
cdkn2A/B
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
     
 0.585
mier1
Mesoderm induction early response 1b, transcriptional regulator.
      
 0.541
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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