Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pou4f3POU domain protein. (351 aa)    
Predicted Functional Partners:
LOC101063222
RING-type domain-containing protein.
      
 0.626
LOC101067553
PNPLA domain-containing protein.
      
 0.624
atoh1
Atonal bHLH transcription factor 1a.
    
 
 0.605
LOC101061072
Uncharacterized protein.
      
 0.599
LOC101069021
Peripherin 2a (retinal degeneration, slow).
      
 0.568
atoh7
Atonal bHLH transcription factor 7.
    
 
 0.547
LOC101079595
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
     
  0.546
LOC101074421
Retinal outer segment membrane protein 1a.
      
 0.517
ENSTRUP00000076723
annotation not available
      
 0.517
ift88
Intraflagellar transport 88 homolog.
      
 0.512
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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