Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Fam172aFamily with sequence similarity 172 member A. (476 aa)    
Predicted Functional Partners:
LOC101062906
Argonaute RISC component 1; Belongs to the argonaute family.
   
 
 0.761
plac8l1
PLAC8 like 1.
      
 0.744
LOC101078091
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
   
 
 0.727
LOC101067386
Argonaute RISC catalytic component 3a; Belongs to the argonaute family.
   
 
 0.727
ago3
Uncharacterized protein; Belongs to the argonaute family.
   
 
 0.727
slf1
SMC5-SMC6 complex localization factor protein 1.
      
 0.706
cpped1
Calcineurin-like phosphoesterase domain containing 1.
      
 0.700
rsrc2
Arginine/serine-rich coiled-coil 2.
      
 0.672
fbxo38
F-box protein 38.
    
 
 0.560
rnpc3
RNA-binding region (RNP1, RRM) containing 3.
      
 0.552
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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