Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2SEC0_TAKRUUncharacterized protein. (1227 aa)    
Predicted Functional Partners:
wdhd1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.822
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 0.788
tipin
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.777
timeless
Timeless circadian clock.
   
 
 0.768
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.766
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.763
chek2
Checkpoint kinase 2.
    
 
 0.754
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.744
Mcm9
MCM_OB domain-containing protein.
   
 0.744
ENSTRUP00000053968
Uncharacterized protein.
   
 0.735
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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