Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sec11aSignal peptidase complex catalytic subunit SEC11. (179 aa)    
Predicted Functional Partners:
ENSTRUP00000075769
Signal peptidase complex subunit 2.
   
 0.987
spcs1
Signal peptidase complex subunit 1.
   
 0.985
spcs3
Signal peptidase complex subunit 3.
   
 0.981
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
 
 
    0.882
GRPR
Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.822
grpr
Gastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.822
nmbr
Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.751
LOC101062378
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.646
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.646
ENSTRUP00000085478
Neuromedin Bb.
     
 0.641
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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