STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCHD3Patched domain containing 3. (491 aa)    
Predicted Functional Partners:
LOC101069326
YME1-like 1b.
      
 0.655
LOC101072736
RAB18B, member RAS oncogene family.
     
 0.604
cables1
Cdk5 and Abl enzyme substrate 1.
      
 0.561
wdr74
WD repeat domain 74.
      
 0.542
gata6
GATA binding protein 6.
   
  
 0.459
msgn1
Mesogenin 1.
      
 0.450
mib2
Mindbomb E3 ubiquitin protein ligase 2.
      
 0.436
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
      
 0.426
smc6
Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).
      
 0.424
dvl3
Dishevelled segment polarity protein 3a.
    
 
 0.408
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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