Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTCHD3Patched domain containing 3. (491 aa)    
Predicted Functional Partners:
LOC101072736
RAB18B, member RAS oncogene family.
     
 0.708
LOC101069326
YME1-like 1b.
      
 0.703
sppl3
Signal peptide peptidase 3.
      
 0.701
wdr74
WD repeat domain 74.
      
 0.697
LOC101077435
Si:dkey-222f2.1; Belongs to the intermediate filament family.
      
 0.632
ranbp1
RAN binding protein 1.
      
 0.619
klhl14
Kelch-like family member 14.
      
 0.611
SYDE2
Synapse defective Rho GTPase homolog 2.
      
 0.600
CDR2L
Cerebellar degeneration related protein 2 like.
      
 0.599
LOC101068367
Cerebellar degeneration-related protein 2-like.
      
 0.599
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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