Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101061436Cytochrome P450, family 4, subfamily V, polypeptide 8; Belongs to the cytochrome P450 family. (516 aa)    
Predicted Functional Partners:
LOC101077941
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
 
 
 
 0.927
LOC101072026
Cytochrome b5 reductase 4.
   
 
 0.770
LOC101079691
Adenylate kinase 7a.
      
 0.700
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 0.673
LOC101075863
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
 
0.638
LOC101069992
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
 
 0.632
LOC101077599
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
 
 0.632
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.623
aasdh
Aminoadipate-semialdehyde dehydrogenase.
  
 0.613
LOC101063139
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 
0.605
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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