Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074197Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (581 aa)    
Predicted Functional Partners:
LOC101066095
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.787
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 
 0.731
dhh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.712
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.712
gpc4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
0.697
gpc2
Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
0.676
LOC101063580
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.668
extl3
Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
     
 0.628
LOC101061589
Notum pectinacetylesterase 2.
    
 0.609
LOC101062420
Notum, palmitoleoyl-protein carboxylesterase.
    
 0.609
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.