Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101067632Carbonic anhydrase XVI b. (1408 aa)    
Predicted Functional Partners:
lum
Lumican.
    
 0.707
PTPN14
Tyrosine-protein phosphatase non-receptor type 14 isoform X1.
    
 0.678
LOC101071528
Macrophage stimulating 1 receptor a.
    
 0.662
mst1r
Macrophage stimulating 1 receptor b.
    
 0.662
met
Uncharacterized protein.
    
 0.662
ENSTRUP00000054856
CASP2 and RIPK1 domain containing adaptor with death domain.
      
 0.654
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 
 0.642
mcm7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 
 0.637
cntn2
Contactin 2.
    
 0.634
htr5a
G_PROTEIN_RECEP_F1_2 domain-containing protein.
     
 0.615
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.