Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tlcd4TLC domain containing 4a. (287 aa)    
Predicted Functional Partners:
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
    
 
 0.664
ccdc189
Uncharacterized protein.
    
 
 0.597
ENSTRUP00000083273
Uncharacterized protein.
    
 
 0.597
dpy30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 
 0.568
rassf3
Ras association domain family member 3.
      
 0.542
rgs7bp
Regulator of G protein signaling 7 binding protein a.
      
 0.475
ercc6l
Excision repair cross-complementation group 6-like.
   
 
 0.458
LOC101062594
Si:dkey-69o16.5.
      
 0.454
nrip2
Nuclear receptor interacting protein 2.
      
 0.444
sbf2
SET binding factor 2.
      
 0.441
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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