Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM135Transmembrane protein 135. (451 aa)    
Predicted Functional Partners:
tmem115
Transmembrane protein 115.
      
 0.702
pxmp4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.695
ccdc25
Coiled-coil domain containing 25.
      
 0.637
ENSTRUP00000075246
annotation not available
      
 0.611
ubl7
Ubiquitin-like 7b (bone marrow stromal cell-derived).
      
 0.609
pex6
Peroxisomal biogenesis factor 6.
      
 0.608
ndufaf6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
      
 0.576
LOC101068307
G-patch domain-containing protein.
      
 0.571
tmub1
Transmembrane and ubiquitin-like domain containing 1.
      
 0.568
LOC101073714
ATP-binding cassette, sub-family D (ALD), member 2.
   
  
 0.521
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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