Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
tlr5TIR domain-containing protein; Belongs to the Toll-like receptor family. (884 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.992
LOC101062562
Uncharacterized protein.
  
  
 
0.902
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.794
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.769
LOC101061773
Interleukin-1 receptor-associated kinase 1.
    
 0.760
tlr1
Toll-like receptor 1.
   
 
0.743
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
0.702
il1b
Interleukin-1; Belongs to the IL-1 family.
   
  
 0.700
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.691
il10
Interleukin 10.
   
 
 0.651
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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