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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
depdc1DEP domain containing 1a. (827 aa)    
Predicted Functional Partners:
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
     
 0.595
abi2
Abl-interactor 2b.
   
 
 0.491
myo9b
Myosin IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.478
LOC101075743
Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.478
myo9a
Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.478
LOC101061902
Unconventional myosin-IXb-like isoform X1.
   
 0.478
dock4
Dedicator of cytokinesis 4b; Belongs to the DOCK family.
   
 
  0.468
LOC101071221
Protocadherin b.
     
 0.461
anln
Anillin, actin binding protein.
   
 
 0.438
LOC105418333
Anillin domain-containing protein.
   
 
 0.438
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.