Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wsb1WD repeat and SOCS box-containing protein 1; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (427 aa)    
Predicted Functional Partners:
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
   
 0.891
cul5
Cullin 5a; Belongs to the cullin family.
    
 0.882
LOC101069329
KAT8 regulatory NSL complex subunit 3.
    
 0.873
LOC101074738
Retinoblastoma binding protein 5.
   
 0.873
LOC101070909
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.848
LOC101061441
CXXC finger protein 1b.
    
 0.842
kat14
Lysine acetyltransferase 14.
    
  0.840
yeats2
YEATS domain containing 2.
    
 0.837
hcfc2
Host cell factor C2.
    
 0.831
LOC101079994
Host cell factor C1a.
    
 0.831
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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