Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101065819Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (449 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.942
frat2
Glycogen synthase kinase binding protein.
    
 0.874
apc
APC regulator of WNT signaling pathway.
    
 0.868
LOC101062949
Adenomatous polyposis coli protein 2-like isoform X1.
    
 0.868
nfe2l2
Nuclear factor, erythroid 2-like 2a.
    
 0.866
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
   
 0.854
fbxw11
F-box and WD repeat domain containing 11b.
    
 0.839
prune1
Prune exopolyphosphatase.
    
 
 0.817
ENSTRUP00000070805
Transcriptional regulator Myc-like isoform X1.
    
 0.813
LOC101079931
Junction plakoglobin a.
    
 0.811
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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