Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101066074Thioredoxin domain-containing protein. (441 aa)    
Predicted Functional Partners:
tmx1
Thioredoxin-related transmembrane protein 1.
   
 
 0.706
unc50
Protein unc-50 homolog.
      
 0.609
SCCPDH
Saccharopine dehydrogenase a, tandem duplicate 1.
      
 0.577
LOC101067185
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
    
 
 0.530
LOC101071384
NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.522
LOC101069670
NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.522
LOC101070859
Calnexin.
   
 0.518
LOC101072026
Cytochrome b5 reductase 4.
  
 0.518
LOC101069714
Uncharacterized protein.
   
 0.515
GET1
Guided entry of tail-anchored proteins factor 1.
      
 0.510
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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