Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tecpr2Tectonin beta-propeller repeat containing 2. (1313 aa)    
Predicted Functional Partners:
vps41
VPS41 subunit of HOPS complex.
   
   0.940
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 
 0.920
vps18
VPS18 core subunit of CORVET and HOPS complexes.
    
 
 0.880
asmtl
Acetylserotonin O-methyltransferase-like.
      
 0.746
vps33a
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.738
vps33b
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.738
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
    
 
 0.724
hps3
Hermansky-Pudlak syndrome 3 protein isoform X1.
   
 
 0.664
epg5
Ectopic P-granules autophagy protein 5 homolog (C. elegans).
   
  
 0.650
trappc11
Trafficking protein particle complex 11.
      
 0.645
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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