LOC101074125 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC101074125

Vacuole membrane protein 1. (405 aa)

Predicted Functional Partners:

becn1

0.953

atg13

0.947

auts2

0.683

tmem41b

0.652

gas6

0.588

LOC101071213

0.570

med13

0.570

ei24

0.520

atg12

0.518

epg5

0.517

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101071213	LOC101074125	ENSTRUP00000018298	ENSTRUP00000012045	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Vacuole membrane protein 1.	0.570
LOC101071213	auts2	ENSTRUP00000018298	ENSTRUP00000059308	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Activator of transcription and developmental regulator AUTS2 a.	0.566
LOC101071213	gas6	ENSTRUP00000018298	ENSTRUP00000067170	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Growth arrest-specific 6.	0.612
LOC101071213	med13	ENSTRUP00000018298	ENSTRUP00000072863	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.547
LOC101074125	LOC101071213	ENSTRUP00000012045	ENSTRUP00000018298	Vacuole membrane protein 1.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.570
LOC101074125	atg12	ENSTRUP00000012045	ENSTRUP00000078987	Vacuole membrane protein 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.518
LOC101074125	atg13	ENSTRUP00000012045	ENSTRUP00000066313	Vacuole membrane protein 1.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.947
LOC101074125	auts2	ENSTRUP00000012045	ENSTRUP00000059308	Vacuole membrane protein 1.	Activator of transcription and developmental regulator AUTS2 a.	0.683
LOC101074125	becn1	ENSTRUP00000012045	ENSTRUP00000062049	Vacuole membrane protein 1.	Beclin 1.	0.953
LOC101074125	ei24	ENSTRUP00000012045	ENSTRUP00000010465	Vacuole membrane protein 1.	EI24 autophagy associated transmembrane protein.	0.520
LOC101074125	epg5	ENSTRUP00000012045	ENSTRUP00000029430	Vacuole membrane protein 1.	Ectopic P-granules autophagy protein 5 homolog (C. elegans).	0.517
LOC101074125	gas6	ENSTRUP00000012045	ENSTRUP00000067170	Vacuole membrane protein 1.	Growth arrest-specific 6.	0.588
LOC101074125	med13	ENSTRUP00000012045	ENSTRUP00000072863	Vacuole membrane protein 1.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.570
LOC101074125	tmem41b	ENSTRUP00000012045	ENSTRUP00000044625	Vacuole membrane protein 1.	Transmembrane protein 41B.	0.652
atg12	LOC101074125	ENSTRUP00000078987	ENSTRUP00000012045	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Vacuole membrane protein 1.	0.518
atg12	atg13	ENSTRUP00000078987	ENSTRUP00000066313	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.893
atg12	becn1	ENSTRUP00000078987	ENSTRUP00000062049	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Beclin 1.	0.980
atg12	epg5	ENSTRUP00000078987	ENSTRUP00000029430	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ectopic P-granules autophagy protein 5 homolog (C. elegans).	0.614
atg13	LOC101074125	ENSTRUP00000066313	ENSTRUP00000012045	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Vacuole membrane protein 1.	0.947
atg13	atg12	ENSTRUP00000066313	ENSTRUP00000078987	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.893