Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usp4Ubiquitin carboxyl-terminal hydrolase. (1001 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.975
sart3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.957
usp14
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.923
rps27a
Ribosomal protein S27a.
    
 0.801
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
 0.796
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.785
smad3
Mothers against decapentaplegic homolog.
    
 0.781
LOC101074868
MH1 domain-containing protein.
    
 0.781
LOC101072871
Mothers against decapentaplegic homolog.
    
 0.781
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.780
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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