STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dna2DNA replication helicase/nuclease 2. (1376 aa)    
Predicted Functional Partners:
ENSTRUP00000053212
Exonuclease 1.
   
 0.992
blm
BLM RecQ like helicase.
   
 0.982
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.972
atm
TAN domain-containing protein.
   
 0.965
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.962
wdhd1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.952
rad50
RAD50 homolog, double strand break repair protein.
   
 0.948
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 0.947
pif1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
   
 
 0.945
recql5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.940
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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