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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsd17b8Hydroxysteroid (17-beta) dehydrogenase 8. (280 aa)    
Predicted Functional Partners:
cbr4
Carbonyl reductase 4.
  
 
0.996
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.960
hsd17b3
Hydroxysteroid (17-beta) dehydrogenase 3.
 
 0.955
fasn
Coiled-coil domain containing 57.
  
 0.934
LOC101073188
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.931
cyp17a2
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.928
cyp17a1
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.928
pfcyp19a
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.926
LOC101074542
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 
 0.925
srd5a3
Steroid 5 alpha-reductase 3.
     
 0.924
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.