Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
f2rCoagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.998
LOC101071876
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.951
gna12
G protein subunit alpha 12.
    
 0.951
LOC101065558
Uncharacterized protein.
    
 0.951
pdcd6ip
Programmed cell death 6 interacting protein.
    
   0.849
plg
Uncharacterized protein; Belongs to the peptidase S1 family.
    
 0.835
LOC101070011
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.761
LOC101066066
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.760
LOC101066291
Uncharacterized protein.
    
 0.760
LOC101063826
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.760
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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