NPC1L1 protein (Takifugu rubripes) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Score

NPC1L1

SSD domain-containing protein. (1353 aa)

Predicted Functional Partners:

npc2

0.931

srebf1

0.836

srebf2

0.836

abcg5

0.680

insig2

0.648

insig1

0.648

abcg8

0.647

LOC101071379

0.637

mbtps1

0.635

LOC101065380

0.545

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101065380	NPC1L1	ENSTRUP00000003701	ENSTRUP00000012302	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	SSD domain-containing protein.	0.545
LOC101071379	NPC1L1	ENSTRUP00000069294	ENSTRUP00000012302	MYCN proto-oncogene, bHLH transcription factor.	SSD domain-containing protein.	0.637
NPC1L1	LOC101065380	ENSTRUP00000012302	ENSTRUP00000003701	SSD domain-containing protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.545
NPC1L1	LOC101071379	ENSTRUP00000012302	ENSTRUP00000069294	SSD domain-containing protein.	MYCN proto-oncogene, bHLH transcription factor.	0.637
NPC1L1	abcg5	ENSTRUP00000012302	ENSTRUP00000023704	SSD domain-containing protein.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.680
NPC1L1	abcg8	ENSTRUP00000012302	ENSTRUP00000071734	SSD domain-containing protein.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.647
NPC1L1	insig1	ENSTRUP00000012302	ENSTRUP00000050225	SSD domain-containing protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	0.648
NPC1L1	insig2	ENSTRUP00000012302	ENSTRUP00000036557	SSD domain-containing protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.648
NPC1L1	mbtps1	ENSTRUP00000012302	ENSTRUP00000056047	SSD domain-containing protein.	Membrane-bound transcription factor peptidase, site 1.	0.635
NPC1L1	npc2	ENSTRUP00000012302	ENSTRUP00000046752	SSD domain-containing protein.	Niemann-Pick disease, type C2.	0.931
NPC1L1	srebf1	ENSTRUP00000012302	ENSTRUP00000020514	SSD domain-containing protein.	Sterol regulatory element binding transcription factor 1.	0.836
NPC1L1	srebf2	ENSTRUP00000012302	ENSTRUP00000080294	SSD domain-containing protein.	Sterol regulatory element binding transcription factor 2.	0.836
abcg5	NPC1L1	ENSTRUP00000023704	ENSTRUP00000012302	ATP-binding cassette, sub-family G (WHITE), member 5.	SSD domain-containing protein.	0.680
abcg5	abcg8	ENSTRUP00000023704	ENSTRUP00000071734	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.999
abcg5	srebf1	ENSTRUP00000023704	ENSTRUP00000020514	ATP-binding cassette, sub-family G (WHITE), member 5.	Sterol regulatory element binding transcription factor 1.	0.528
abcg5	srebf2	ENSTRUP00000023704	ENSTRUP00000080294	ATP-binding cassette, sub-family G (WHITE), member 5.	Sterol regulatory element binding transcription factor 2.	0.528
abcg8	NPC1L1	ENSTRUP00000071734	ENSTRUP00000012302	ATP-binding cassette, sub-family G (WHITE), member 8.	SSD domain-containing protein.	0.647
abcg8	abcg5	ENSTRUP00000071734	ENSTRUP00000023704	ATP-binding cassette, sub-family G (WHITE), member 8.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.999
abcg8	srebf1	ENSTRUP00000071734	ENSTRUP00000020514	ATP-binding cassette, sub-family G (WHITE), member 8.	Sterol regulatory element binding transcription factor 1.	0.526
abcg8	srebf2	ENSTRUP00000071734	ENSTRUP00000080294	ATP-binding cassette, sub-family G (WHITE), member 8.	Sterol regulatory element binding transcription factor 2.	0.526