Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tbr1T-box brain transcription factor 1b. (677 aa)    
Predicted Functional Partners:
zic1
Zic family member 1 (odd-paired homolog, Drosophila).
    
 
 0.789
egr2
Early growth response 2b.
   
 
 0.783
mixl1
Mix paired-like homeobox.
   
 0.756
cask
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
 
 0.723
egr3
Early growth response 3.
    
 
 0.711
Plagl2
Pleiomorphic adenoma gene-like 2.
    
 
 0.702
snx33
Sorting nexin.
      
 0.700
enc1
Ectodermal-neural cortex 1.
    
 
 0.689
satb2
DNA-binding protein SATB.
   
 
 0.665
LOC101068612
Forkhead box H1.
     
 0.641
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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