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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spcs3Signal peptidase complex subunit 3. (180 aa)    
Predicted Functional Partners:
ENSTRUP00000075769
Signal peptidase complex subunit 2.
   
 0.988
spcs1
Signal peptidase complex subunit 1.
   
 0.985
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.973
ENSTRUP00000052302
Uncharacterized protein.
   
 0.959
immp2l
Mitochondrial inner membrane protease subunit.
   
 0.824
itfg2
Integrin alpha FG-GAP repeat containing 2.
   
 0.824
LOC101069895
X-ray repair complementing defective repair in Chinese hamster cells 4.
   
 0.824
immp1l
Mitochondrial inner membrane protease subunit.
   
 0.824
auh
AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
    0.666
rpn2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.665
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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