Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spcs3Signal peptidase complex subunit 3. (180 aa)    
Predicted Functional Partners:
ENSTRUP00000075769
Signal peptidase complex subunit 2.
   
 0.999
spcs1
Signal peptidase complex subunit 1.
   
 0.999
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.981
ENSTRUP00000052302
Uncharacterized protein.
   
 0.962
immp2l
Mitochondrial inner membrane protease subunit.
   
 0.864
immp1l
Mitochondrial inner membrane protease subunit.
   
 0.864
mrps18b
Mitochondrial ribosomal protein S18B.
      
 0.725
ddost
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 0.717
itfg2
Integrin alpha FG-GAP repeat containing 2.
   
 0.717
LOC101069895
X-ray repair complementing defective repair in Chinese hamster cells 4.
   
 0.717
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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