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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dhrs1Dehydrogenase/reductase (SDR family) member 1. (310 aa)    
Predicted Functional Partners:
rrn3
RRN3 homolog, RNA polymerase I transcription factor.
   
  
 0.700
dhrs7b
Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.685
eci2
Enoyl-CoA delta isomerase 2.
  
 0.671
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit.
    
 
 0.650
scp2
Sterol carrier protein 2a; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.637
tep1
Telomerase protein component 1.
   
 
 0.598
iyd
Iodotyrosine deiodinase.
   
 
 0.578
spc25
SPC25 component of NDC80 kinetochore complex.
    
 
 0.539
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 0.527
cat
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.520
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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